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Saturday, 22 November 2014

Stereochemistry of cis/trans Decalins




A useful application of long range couplings for the assignment of ring-fusion stereochemistry in decalin ring system bearing an angular methyl group has been developed (Williamson, K. L.; Howell, T.; Spencer, T. A. J. Am. Chem. Soc. 196688, 325). In the trans-decalins, there are usually several ideal W-pathways for long range coupling between the methyl group and axial protons. In cis-decalins, there are fewer or no such pathways. Thus in a pair of cis/trans isomers, the methyl group in the trans isomer will usually be broader (or will actually show splitting), whereas the cis isomer will have a sharper (unsplit) methyl group.
  

1 comment:

  1. you are clear my mind actually after reading your article i got clear my complete doubt. thanks for such easy understanding post. Sharing on What is the difference between cis and trans isomers? for future aspect at here http://electrotopic.com/what-is-the-difference-between-cis-and-trans-isomers/

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