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Tuesday, 15 October 2019

Catalyst- and additive-free Baeyer–Villiger-type oxidation of α-iodocyclopentenones to α-pyrones: using air as the oxidant

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An efficient synthetic approach for the synthesis of α-pyrones  via  Baeyer–Villiger-type oxidation of α-iodocyclopentenones through a c...
137 comments:
Tuesday, 10 September 2019

Ethyl 4-(4-cyclopropyl-2-oxo-2H-pyran-6-yl)butanoate

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Catalyst- and Additive-Free Baeyer−Villiger-type Oxidation of α-Iodocyclopentenones to α-Pyrones: Using Air as the Oxidant Yuanyuan Zh...
69 comments:
Thursday, 5 September 2019

4-(trifluoromethoxy)benzyl trichloroacetimidate:

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4-(Trifluoromethoxy)benzyl Trichloroacetimidate To a stirred suspension of NaH (60%, 127 mg, 3.45 mmol) in  t -BuOMe (100 mL)...
1 comment:

(R)-3-Chloro-2-hydroxypropyl-4-methoxybenzoate

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( R )-3-Chloro-2-hydroxypropyl-4-methoxybenzoate  10 To a stirred solution of ( R )-3-chloro-1,2-propanediol (6.61 g, 59.8 mmol)...
2 comments:
Wednesday, 4 September 2019

Pretomanid

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Pretomanid read syn   https://newdrugapprovals.org/2019/09/04/pretomanid-%e3%83%97%e3%83%ac%e3%83%88%e3%83%9e%e3%83%8b%e3%83%89/ T...
4 comments:
Tuesday, 6 August 2019

Verubecestat Impurity 10

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Verubecestat Verubecestat Impurity 10 1H NMR (600 MHz, Acetonitrile-d3) δ 9.86 (s, 1H), 8.21 (d, J = 3.0 Hz, 1H), 8.02 (dd, J ...
Monday, 8 April 2019

AB 680 « New Drug Approvals

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AB 680 « New Drug Approvals : AB 680 C20H24ClFN4O9P2, 580.827 g/mol Cas 2105904-82-1 1H-Pyrazolo[3,4-b]pyridin-4-amine, 6-chloro-N-[(1S)-1-(...
14 comments: