DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Monday 16 September 2013

Solid state NMR technique takes on Taxol

Taxol structure

Taxol's active conformation has proved a puzzle


US scientists have developed a new technique for investigating the biologically active forms of the anticancer drug Taxol.
David Grant at the University of Utah, Salt Lake City, and co-workers have used novel solid state NMR techniques to establish the structure of a unique conformation of paclitaxel - more commonly known as Taxol.

NMR IN DRUG DISCOVERY

  1. [PDF]

    NMR in Drug Discovery

    www.bioc.aecom.yu.edu/labs/.../nmr/.../Lecture_DrugDiscovery_2010.p...
    Apr 23, 2010 - 1. COURSE#1022: Biochemical Applications of NMR Spectroscopy http://www.bioc.aecom.yu.edu/labs/girvlab/nmr/course/. NMR in Drug ...


    CLICK BELOW

http://www.bioc.aecom.yu.edu/labs/girvlab/nmr/course/COURSE_2012/Lecture_DrugDiscovery_2010.pdf

NMR determination of enantiomeric purity



wait for loading....................
or
directly view at wenku baidu

view at
http://wenku.baidu.com/view/3189c831ee06eff9aef80750.html

Wednesday 11 September 2013

Unravelling stereochemistry via mass spectrometry

AAAS/Science
The new technique can determine the stereochemical configuration of a molecule by the way it breaks apart © Science/AAAS
News item thumbnail




Technique reveals a molecule’s chirality without separating the enantiomers or growing pure crystals

READ ALL AT
http://www.rsc.org/chemistryworld/2013/09/molecules-stereochemistry-chirality-mass-spectrometry