[(3-cyano-5-phenyl -1H- pyrrol-2-yl) thio] acetic acid

 [(3-cyano-5-phenyl -1H- pyrrol-2-yl) thio] acetic acid




 (2-phenyl-2-oxoethyl) malononitrile (1. 0g, 54. 3mmol), methanol (150ml) and thioglycolic acid (6. 0g, 52. 6_〇1) loading into the reactor, and the mixture was heated at reflux for 0.5 hours. Let the mixture was cooled and stirred for 0.5 hours at room temperature and was stirred under ice-cooling 0.5 hours. The crystals were collected by filtration. With ethyl acetate (60ml) washing the wet crystals and reduced pressure, 50 ° C and dried to give the title compound (8. 8g, yield 60%).

 
  i-NMRGOOMHz, TMS, DMS0-d6) δ (ppm):. 7 60 (d, J = 8. 0Hz, 2H), 7 39 (t, J = 7. 6Hz, 2H), 7.. 26-7. 21 (m, 1H), 6. 66 (s, 1H), 2. 51 (s, 2H).
 
high-resolution mass spectrometry (FAB) (C13H1QN202S)
calculated 257. 0835 [Μ-ΗΓ
measurements 257. 0390 [Μ-ΗΓ




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RAJKOT, GUJARAT, INDIA 

Rajkot

City in India

Rajkot is the fourth largest city in the state of Gujarat, India, after Ahmedabad, Surat, and Vadodara. Rajkot is the center of the Saurashtra region of Gujarat. Wikipedia

 

 

 

 
 

 

 

 

 


 

 

 
 

 
 

 

 

 

 


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N-4-Dimethyl-N-[(trifluoromethyl)sulfanyl]benzene-1-sulfonamide

purified by flash chromatography (cyclohexane/ethyl acetate: 99:1 to 96:4) to afford BB23 (84.22 g, 88%, light yellow solid).

¹H NMR (400 MHz, CDCl₃) δ = 7.75 (m, 2H), 7.35 (m, 2H), 3.31 (s, 3H), 2.44 (s, 3H).

¹³C NMR (101 MHz, CDCl₃) δ = 145.1, 134.3, 130.1, 129.0 (q, ³J(C,F) = 316 Hz), 127.9, 43.8, 21.7.

¹⁹F NMR (376 MHz, CDCl₃) δ = −50.34 (s, 3F).

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Wayanad, Calicut, kerala, india

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NMR Examples

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Rehovot, Israel

Rehovot
City in Israel
Rehovot is a city in the Center District of Israel, about 20 kilometers south of Tel Aviv. According to the Israel Central Bureau of Statistics, at the end of 2014 the city had a total population of 128,900. Wikipedia

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