Dacomitinib

(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl}-4-(1-piperidinyl)-2-butenamide

4-Piperidin-1-yl-but-2-enoic acid [4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yl]-amide

1042385-75-0

pf299804…… pfizer

EGFR (HER1; erbB1) Inhibitors
HER4 (erbB4) Inhibitors
HER2 (erbB2) Inhibitors

Molecular formula:C24H25ClFN5O2
Molecular mass:469.95

syn.........http://newdrugapprovals.org/2014/04/09/dacomitinib-in-phase-3-for-lung-non-small-cell-nsclc-cancer/

1H NMR

COSY PREDICTION

1H NMR PREDICT
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide NMR spectra analysis, Chemical CAS NO. 1110813-31-4 NMR spectral analysis, (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide H-NMR spectrum