(R)-2-Hydroxy-N-(4-nitrophenethyl)-2-phenylacetamide

Molecular Formula:	C16H16N2O4
Molecular Weight:	300.314 g/mol

521284-19-5; (R)-2-Hydroxy-N-(4-nitrophenethyl)-2-phenylacetamide; (R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide; (2r)-2-hydroxy-n-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide; 

Concise Synthesis of Key Intermediate of Mirabegron via a Mixed Anhydride Method

Qi-Long Zhang, Zhi-Yuan Zhuang, Qing-Dong Liu, Zhan-Ming Zhang, Fu-Xu Zhan*, and Geng-Xiu Zheng*

School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, Shandong, P. R. China

Org. Process Res. Dev., Article ASAP

DOI: 10.1021/acs.oprd.6b00231

Publication Date (Web): October 13, 2016

Copyright © 2016 American Chemical Society

*E-mail: chm_zhanfx@ujn.edu.cn. Tel.: +8653182765841., *E-mail: chm_zhenggx@ujn.edu.cn.

http://pubs.acs.org/doi/abs/10.1021/acs.oprd.6b00231






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Patent CN103193730A - Synthesis method of mirabegron - Google Patents

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Figure CN103193730AD00051

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c1(ccccc1)[C@@H](O)C(=O)NCCc2ccc(cc2)[N+]([O-])=O