Applications of Mass Spectrometry...on November 20, 2014 at CSIR-Indian Institute of Chemical Technology, Hyderabad, India

Dr Sanjay Bajaj
Managing Director at Select Biosciences India

Limited seats available for In-Lab Workshop on Mass Spectrometry. Register today to avoid disappointments for "Applications of Mass Spectrometry" conference scheduled to be held on Nov 20, 2014 at CSIR-IICT, Hyderabad. For more information follow the linkhttp://lnkd.in/bJg6ai6

or see
http://selectbiosciences.com/conferences/index.aspx?conf=AMS14

SELECTBIO welcome you all at the International Conference on Applications of Mass Spectrometry scheduled to be held on November 20, 2014 at CSIR-Indian Institute of Chemical Technology, Hyderabad, India

Mass Spectrometry, has now become the most powerful analytical tool in almost every scientific discipline. This conference focuses on the instrumentation, tools, interpretation of results, applications, advances and new perspectives of Mass Spectrometry in the fields of Pharmaceuticals, Clinical, Genomics, Proteomics, Forensic, Environmental sciences etc. Attending this event will provide you with excellent opportunity for networking with like minded peers, helping you to build new relationships and optimize your workflow. 

This event is co-located with specialized event related to use of Mass Spectrometry in Pharmaceutical Analysis i.e.Advances in Forced Degradation Studies of Pharmaceuticals. Running alongside the conference will be an exhibition covering the latest technological advances and associated services within this field. 

Confirmed Speakers to date

Saranjit Singh, Professor/Head, National Institute of Pharmaceutical Education and Research
Jurgen H Gross, Head Mass Spectrometry Lab, Heidelberg University
R Srinivas, Head, NCMS, Indian Institute of Chemical Technology
Utpal Tatu, Professor, Indian Institute of Science
Mariappanadar Vairamani, Dean, SRM University

Call for Posters You can also present your research on a poster while attending the meeting. Submit an abstract for consideration now! Poster Submission Deadline: 31 October 2014 Agenda Topics Applications in Genomics, Proteomics, Metabolomics & Lipidomics In Lab Mass Spectrometry Workshop Mass Spectrometry – Instrumentation and tools Mass Spectrometry for Qualitative and Quantitative Analysis of Pharmaceuticals Mass Spectrometry-Current Approaches and New Vistas Sponsorship and Exhibition Opportunities Maninderjit Singh, Exhibition Manager mjsingh@selectbio.com 7696225050

Importance of Mass Spectrometry for Newborn Screening

Importance of Mass Spectrometry for Newborn Screening

Professor G. la Marca speaks about the importance of newborn screening and why it is more than a useful biochemical test
Read more

What does newborn screening mean?

Newborn screening (NBS) is known to be a biochemical test that enables the identification of many inborn errors of metabolism (IEM) a few days after birth. But considering that NBS requires expert lab technicians, chemists, biologists, nutritionists, and medical specialists for metabolic disorders, it cannot only be considered a useful biochemical test, rather it should be considered a complex and integrated program.  READ AT



http://www.chemistryviews.org/details/ezine/6425361/Importance_of_Mass_Spectrometry_for_Newborn_Screening.html

Cinacalcet Hydrochloride spectral data

 


IR (KBr) (cm^–1): 3447, 2964, 1587, 800, 776. 


MS: m/z = 358.3 [M + H] ⁺.




¹H NMR (CDCl₃): δ 1.98 (d, J = 6.7 Hz, 3H), 2.2–2.35 (m, 2H), 2.46–2.60 (m, 2H), 2.55–2.85 (m, 2H), 5.10–5.25 (m, 1H), 7.16–7.26 (m, 3H), 7.31–7.33 (d, J = 7.4 Hz 1H), 7.54–7.65 (m, 3H), 7.88–7.97 (m, 3H), 8.23 (d, J = 7.2 Hz,1H). 

  
¹³C NMR (DMSO-d₆): δ 19.99 (CH₃), 27.01 (CH₂), 31.50 (CH₂), 44.65 (CH₂), 52.05 (CH), 122.58, 122.69, 122.73, 124.42, 124.74, 124.67, 125.50, 126.10, 126.88, 128.83, 128.89, 129.32, 130.28, 132.39, 133.32, 134.10, 142.25.
 http://pubs.acs.org/doi/full/10.1021/op300164y


........................................................
next set
  IR (KBr): 3427 (broad, –NH–), 2951, 2797, 2750, 2712, 1587, 1450, 1327, 1165, 1128, 1072, 798, 775 cm⁻¹;  

¹H NMR (DMSO-d₆/TMS) δ 1.67 (d, J = 6.6, 3H, –CH₃), 1.99 (quintet, 2H, –CH₂), 2.70 (m, 2H, –CH₂), 2.93 (m, 2H, –CH₂), 5.30 (q, 1H, –CH), 7.46–7.61 (m, 7H, ArH), 7.95–8.03 (m, 3H, ArH), 8.23 (d, J = 8.0, 1H, ArH), 9.36 (s, 1H, –NH) and 10.04 (s, 1H, HCl); 

 ¹³C NMR (DMSO-d₆/TMS) δ 142.61, 134.48, 133.70, 132.80, 130.64, 129.74, 129.58,129.28, 127.29, 126.54, 125.90, 125.08, 124.67, 123.16, 122.98, 52.37, 45.04, 31.84, 27.44, 20.30; 

MS m/z: 358 [M + 1]⁺.
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-8-158

...........................
 IR (KBr) cm⁻¹: 3436, 2962, 2797, 1587, 1450, 1379, 1327, 1166, 1129, 797, 774, 746; 
MS: m/z = 358.79 [M + H] ⁺;  
¹H NMR (400 MHz, DMSO-d₆): δ = 1.67−1.69 (d, 3H), 1.97−2.02 (m, 2H), 2.67−2.69 (t, 4H), 5.27 (q, 1H), 7.44−7.46 (m, 4H), 7.54−7.61 (m, 3H), 7.93−7.99 (m, 2H), 8.026−8.08 (d, J = 7.2 Hz, 1H), 8.20−8.23 (d, J = 7.2 Hz, 1H), 9.46 (s, 1H), 10.17 (s, 1H);  
¹³C NMR (100 MHz, DMSO-d₆): δ = 20.49 (CH₃), 27.50 (CH₂), 32.02 (CH₂), 45.18 (CH₂), 52.60 (CH), 123.06, 123..23, 123.26, 124.94, 125.17, 125.21 (CF₃), 126.0, 126.60, 127.39, 129.35, 129.39, 129.82, 130.79, 132.88, 133.83, 134.58, 142.75; 
Anal. Calcd for C₂₂H₂₃NF₃Cl: C, 67.09; H, 5.84; N, 3.55; Found: C, 66.92; H, 5.68; N, 3.58.
 http://pubs.acs.org/doi/full/10.1021/op200016a

Unravelling stereochemistry via mass spectrometry

The new technique can determine the stereochemical configuration of a molecule by the way it breaks apart © Science/AAAS
	Technique reveals a molecule’s chirality without separating the enantiomers or growing pure crystals READ ALL AT http://www.rsc.org/chemistryworld/2013/09/molecules-stereochemistry-chirality-mass-spectrometry