CAMPHOR

CAMPHOR, 

Molecular Formula: C₁₀H₁₆O 
Molecular Weight: 152.233

InChI=

1/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3

IUPAC Name:

1,7,7-Trimethylnorboran-2-one

CAS Number: 464-48-2

1HNMR

(1R)-(+)-camphor

DEPT

13C

(1R)-(+)-camphor2-Dimensional COSY

(1R)-(+)-camphor2-Dimensional Hector

Examples
• [0039]
  (-)-(1S)-Camphor (2). To a vigorously stirred solution of 600g (3.89 mol) of (-)-borneol in 1.5 L of glacial acetic acid at 0 °C was added 7.5 L of household bleach (Chlorox™) over a period of 1 h. After 30 min the solid (800 g) was collected by filtration and dissolved in 2 L of hexane. The solution was washed with saturated aqueous NaHCO₃ and brine, dried over Na₂SO₄ and concentrated to give 570g (96%) of camphor.
  2: mp: 178-180°C; [α]_D ²⁵=-39 (c=3.0, EtOH), ¹H NMR see Table; ¹³C NMR (100 MHz, CDCl₃) δ (ppm): 9.20, 19.10, 19.74, 27.02, 29.90, 43.05, 43.25, 46.73, 57.64, 219.46.
  

  

  

1,7,7-Trimethylbicyclo[2.2.1]-2-Heptanone
CAS No.:	464-48-2
Synonyms:	(-)-Camphor;
Formula:	C10H16O
Exact Mass:	152.12000

1H NMR PREDICT

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

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KATHMANDU,  NEPAL











































Kathmandu Durbar Square 

NEOSTIGMINE

Neostigmine shows notable UV/VIS absorption at 261nm, 267nm, and 225nm.

Neostigmine's ¹H NMR Spectroscopy reveals shifts at: 7.8, 7.7, 7.4, 7.4, 3.8, and 3.1 parts per million. The higher shifts are due to the aromatic hydrogens. The lower shifts at 3.8ppm and 3.1ppm are due to the electronic withdrawing nature of the tertiary and quarterary nitrogen, respectively.

pnmr of neostigime

13c nmr


HMBC SPECTRUM


IR

Neostigmine, N,N,N-trimethyl-meta-(dimethylcarbomoyloxy)-phenylammonium methylsulfonate, which can be viewed as a simplified analog of physostigmine, is made by reacting 3-dimethylaminophenol with N-dimethylcarbamoyl chloride, which forms the dimethylcarbamate, and its subsequent alkylation using dimethylsulfate forming the desired compound. 

• 43. J.A. Aeschlimann, U.S. Patent 1,905,990 (1933).

Spectral data

Neostigmine shows notable UV/VIS absorption at 261 nm, 267 nm, and 225 nm.^[7]

Neostigmine's ¹H NMR Spectroscopy reveals shifts at: 7.8, 7.7, 7.4, 7.4, 3.8, and 3.1 parts per million. The higher shifts are due to the aromatic hydrogens. The lower shifts at 3.8ppm and 3.1ppm are due to the electronic withdrawing nature of the tertiary and quarterary nitrogen, respectively.^[8]

1. Porst H; Kny L (May 1985). "[The structure of degradation products of neostigmine bromide]". Pharmazie. (in German) 40 (5): 325–8. PMID 4034636.
2. Jump up^ Ferdous, Abu J; Waigh, Roger D (1993). "Application of the WATR technique for water suppression in 1H NMR spectroscopy in determination of the kinetics of hydrolysis of neostigmine bromide in aqueous solution". Journal of Pharmacy and Pharmacology 45 (6): 559–562. doi:10.1111/j.2042-7158.1993.tb05598.x. PMID 8103105

1H NMR PREDICT
NEOSTIGMINE BROMIDE
13C NMR






1H NMR

VLADIVOSTOK