The African pin cushion plant produces large quantities of analgesic compounds...now NMR has demonstrated that one of the primary components is chemically identical to the well-known, synthetic opioid painkiller Tramadol.

Getting to the root of painkiller

The African pin cushion plant produces large quantities of analgesic compounds...now NMR has demonstrated that one of the primary components is chemically identical to the well-known, synthetic opioid painkiller Tramadol. The discovery should serve as a warning to the potential problems of dependency and addiction that might occur with use of so-called natural and herbal medicinal products.

Michel De Waard, Inserm Research Director at the Grenoble Institute of Neurosciences and colleagues report that this is the first time that what was considered to be an entirely synthetic pharmaceutical product is present naturally at high concentration in a plant or other biological source.

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