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Showing posts with label 2′-bipyridin]-6-yl)malonate. Show all posts
Showing posts with label 2′-bipyridin]-6-yl)malonate. Show all posts

Monday, 25 January 2016

Dimethyl 2-(2-Oxo-2H-[1,2′-bipyridin]-6-yl)malonate


  str1 Dimethyl 2-(2-Oxo-2H-[1,2′-bipyridin]-6-yl)malonate (3d)
 
Yellow oil, 27.8 mg (92%);  

1H NMR (400 MHz, CDCl3) δ 8.58 (d, J = 4.7 Hz, 1H), 7.85 (t, J = 7.7, 1H), 7.37 (m, 3H), 6.61 (d, J = 9.3 Hz, 1H), 6.30 (d, J = 7.0 Hz, 1H), 4.31 (s, 1H), 3.67 (s, 6H); 

13C NMR (100 MHz, CDCl3) δ 166.2, 163.1, 150.7, 149.9, 140, 139.8, 138.7, 124.7, 124.5, 121.4, 107.2, 55.0, 53.3.


FT-IR: ν̃ = 3054, 2957, 2927, 2854, 1766, 1734, 1678, 1605, 1545, 1469, 1437, 1396, 1297, 1248, 1205 cm–1;

HRMS: calculated for [M + H]+ C15H15N2O5: 303.0981, found: 303.1007.
str1.png

Friday, 22 January 2016

Dimethyl 2-(5-Chloro-2-oxo-2H-[1,2′-bipyridin]-6-yl)malonate

str1

Dimethyl 2-(5-Chloro-2-oxo-2H-[1,2′-bipyridin]-6-yl)malonate (6i)
Pale Yellow oil, 29.6 mg (88%);  
1H NMR (600 MHz, CDCl3) δ 8.68–8.53 (m, 1H), 7.90 (td, J = 7.8, 1.9 Hz, 1H), 7.42 (m,3H), 6.65 (d, J = 9.9 Hz, 1H), 4.32 (s, 1H), 3.75 (s, 6H);  
13C NMR (150 MHz, CDCl3) δ 164.9, 161.8, 151.0, 150.2, 142.3, 139.0, 137.6, 124.9, 124.5, 122.5, 115.5, 54.6, 53.5; 
FT-IR: ν̃ = 3058, 2959, 2854, 1737, 1671, 1596, 1545, 1467, 1435, 1394, 1367, 1302, 1241, 1210 cm–1
HRMS: calculated for [M + H]+ C15H1435ClN2O5: 337.0591, found 337.0584.
str1




Cambodia




Choeung Ek – This is the National Memorial site for the killing fields. A recommended place to visit. Upon arrival,  when we paid the entrance fee, we received our headsets and audio players. Which allow us to do a self-guided tour around the site. It is a very well-done, a good approach, allowing visitors to stroll along at our own pace and quietly walked on site.

Tuol Sleng Museum
Tuol Sleng Museum
Tuol Sleng Museum – We visited the Tuol Seng Museum after Choeung Ek. We took a half-day tour as recommended by the Hotel owner. At this museum, we were able to see the hard living conditions of the prison and how the prisoners were cruelly tortured. We got the chance to see a few of the ex-prisoners of this prison.

National Museum
National Museum
National Museum of Cambodia in Phnom Penh.  http://www.cambodiamuseum.info/en_information_visitors.html
Central Market
Central Market
Central Market  -Lots of interesting seafood and all types of merchandises are available at the Central Market.
 Russian Market – It is a popular market for both the locals and tourists. which you can shop for clothes, souvenirs, jewellery, gemstones, local food and produce. It is always very fun and interesting to visit the wet market section, which I got to see the wide selection of seafood and meat.
 Local Cambodian Food
Cambodia local restaurant
Cambodia local restaurant
A recommended local restaurant with huge signboard. Serving delicious and cheap food and drinks.
Squid with green pepper
Squid with green pepper
Fresh Squid With Green Pepper. One of best dishes I tasted in Cambodia. The squids are super fresh and the the pepper adds a subtle peppery sweet and spiciness taste. Beautiful.
Stir fried Beef with Ants & Herbs
Stir fried Beef with Ants & Herbs
Stir Fried Beef with Ants & Herbs. dish is interesting to try. the herb taste is a bit too strong for my liking. I can hear the little crunchiness of eating the big and small ants.
Angkor  Beer
Angkor Beer
Angkor Beer. Favourite local Cambodian Beer. Very cheap. Just US$0.50 cent for a glass of draft beer. US 1.80 per jug at a local restaurant. ( Please note: this is the cheapest price, most places will sell at a bit higher than what I have indicated here)
Beef Lok Lak
Beef Lok Lak
Lok Lak – One of the popular local dish in Cambodia, which has a sweet savoury taste which can be of beef, chicken or pork.
Fresh crab with green pepper
Fresh crab with green pepper
Fresh Crabs With Green Pepper is also another great dish to order. Crabs in Cambodia are generally small. but always taste fresh and sweet! Love it.
Fried fish on the fire lake
Fried fish on the fire lake
Fried Fish On The Fire Lake is very interesting. It comes with a huge fried fish poured over with light flavour curry sauce, with a side of vegetable  like cauliflower and cabbage that you can add in to cook on the hot plate. Noodles is also served along with this dish.
Fish Amok
Fish Amok
Fish Amok is a Must-Try dish in Cambodia. There is nothing like it. Not in Thailand, Indonesia, Singapore. The above does not look very appetising.The one I tried in Siem Reap was super delicious. It is made with coconut milk and the local spices like Lemongrass, Tumeric, Galangal, Lime leaves, Amok leaves. It can be fish, chicken or pork.
Tuk Tuk
Tuk Tuk
Tuk Tuk is the most common transport available in Cambodia. It cost about US$2-$3 for short distance.
 Highlights in Siem Reap
Coconut on the move
Coconut on the move
Angkor Archaeological Park
Angkor Archaeological Park
A nice view view in the Angkor Archaeological Park
Nice rice fields
Nice rice fields planted by the local family in the village
Local Village in Angkor Archaeological Park
Cute little boy at a local Village in Angkor Archaeological Park. This was taken when I took the KKO Cycling tour. Do join the tour if you enjoy and like cycling. It is a great way to see the less touristy site of Angkor Wat with a cause.
Baguette Sandwich
Baguette Sandwich
Baguette Sandwich. A popular local breakfast from the street stall. The filling are ham and pork bits with some local sauce. It comes with a light salad too. You can order half instead of ordering one whole baguette. The baguette is really tasty.
Entrance to the South Gate of Angkor Thom
Entrance to the South Gate of Angkor Thom
Angkor Thom is one of the popular starting point to get into the Bayon Temple
Banteay Kdei
Banteay Kdei
Banteay Kdei is built in a similar style to Ta Prohm but much smaller scale.
Banteay Srei
Banteay Srei
Banteay Srei is a very popular site, which is very crowded with tourists. It is built with rose-pink sandstone. Something very different from the other temples. The carving on the temple are very precise and delicate.
Kbal Spean,
Kbal Spean
Interesting carving on the rock that you can see after climbing up 1.5 km in the wood.

Angkor Wat
Angkor Wat
Angkor Wat, the best time to visit is about 2pm when the sun is shining up the temple that you can take great picture. Visiting it in the afternoon is also better with lesser crowd as compared to going in the morning.
There are 1 day pass, 3 day pass and 7 day pass to the Angkor Wat Archaeological Park.
The most recommended pass to take is 3 day pass, when you can take your time to visit sites and places ate a comfortable pace, including Banteay Srei and Kbal Spean on a separate day. You can also try various transport like taking a Tuk Tuk and cycling to see the sites.
It is also recommended to have tour guide to go with you to explain the details, background, history and meaning of the many interesting carvings.

Entrance of Angkor Wat
Entrance of Angkor Wat
Old Market in Siem Reap
Old Market in Siem Reap
Stall at Old Market
Stall at Old Market
Old Market is a great place to shop for souvenirs, nice cotton clothes,  silk and cotton scarf.
Kroma is the local name for the scarf in Cambodia which can be used in many ways. For example the local uses it to protect their head or neck from the sun, to carry items, to wipe away their perspiration from working in the farm. There are many lovely and nice design which makes a very suitable gifts and souvenirs for friends and loved ones.

Fried fish with spring onion and coconut cream with ric
Fried fish with spring onion and coconut cream with rice
A simple and nice lunch at one of the few local restaurant in Old Market. Which offer good local food at reasonable price. Most of the them serve cheap Cambodia draft beer.
BBQ Street stall
BBQ Street stall
Canby Publication Visitor Guide
Canby Publication Visitor Guide
Canby Publication is the most trusted guide book that you should use in Cambodia. It is very useful and helpful with details of the highlights for Angkor Wat, Food, restaurants, Hotels, transport and to beware of scams.
http://www.canbypublications.com/
Kampot Black pepper
Kampot Black pepper
Cambodia is also famously known for it black pepper especially from Kampot. This will make a very good souvenir too.
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