3-[5-(4-Bromophenyl)-2,3-dihydro-1H-pyrrolizin-6-yl]-1,3-dihydro-2H-indol-2-one (7c):
brown powder, 17 %, mp 201-202 C;
1H NMR (200 MHz, DMSO-d6) δ: 10.42 (s, 1H, 1-NH),
7.53 (d, J=8.6 Hz, 2H, 3,5-CH (4-bromobenzoyl)), 7.21 (d, J=8.6 Hz, 2H, 2,6-CH (4
bromobenzoyl), 6.97-6.70 (m, 5H, oxindol), 5.18 (s, 1H, 7-CH), 4.44 (s, 1H, 3-CH), 4.16-3.70
(m, 2H, 3-CH2), 2.80-2.641 (m, 2H, 1-CH2), 2.44-2.28 (m, 2H, 2-CH2);
13C NMR (75 MHz,
DMSO-d6) δ: 178.86 (2-CO), 141.81, 138.34, 135.49, 131.38, 129.47, 129.32, 127.24, 127.05,
124.30, 121.24, 120.21, 116.81, 109.69, 99.23, 46.26, 45.33, 27.31, 24.43.
Anal. calcd. for
C21H17BrN2O (393.28):C 64.13; H 4.36; N 7.12; Found: C 63.90; H 4.39; N 7.18.
MADAYA, SYRIA
Madaya, Syria
Town in Syria
Madaya
is a small mountainous town in Syria, located at an altitude of 1,400
metres. It is a well known holiday resort. It is located about 40
kilometres northwest of Damascus in the Rif Dimashq Governorate and is
home to Lake Barada. Wikipedia
///////
