5-Bromo-3-[5-(3,4-dichlorophenyl)-2,3-dihydro-1H-pyrrolizin-6-yl]-1,3-dihydro-2H
indol-2-one (7a): orange powder, 22%, mp 215-216 C. MS (m/z) (%): 462 (M+, 52), 435 (45),
405 (8), 353 (12), 317 (18), 289 (52), 208 (30), 173 (33), 127 (46), 75 (30), 41 (100). Anal.
calcd. for C21H15BrСl2N2O (462.17): C 54.57; H 3.27; N 6.06; Found: C 54.48; H 3.19; N 6.10.
1595284-00-6
C21 H15 Br Cl2 N2 O
2H-Indol-2-one, 5-bromo-3-[5-(3,4-dichlorophenyl)-2,3-dihydro-1H-pyrrolizin-6-yl]-1,3-dihydro-
- Molecular Weight
- 462.17
NOESY
Beilstein Journal of Organic Chemistry (2014), 10, 117-126
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-10-8
The tentative mechanism for the formation of 7a is outlined in Scheme 3. First, the initially formed spiropyrrolizidine undergoes decarboxylation via ring opening of the spiro cycle. The subsequent enolization of the intermediate leads to the formation of the dihydropyrrolizinyl oxindole system.
7a: orange powder, 22%, mp 215–216 °C. 1H (500 MHz, DMSO-d6) and 13C NMR (125 MHz, DMSO-d6) data are given in Table 3. MS (m/z) (%): 462 (M+, 52), 435 (45), 405 (8), 353 (12), 317 (18), 289 (52), 208 (30), 173 (33), 127 (46), 75 (30), 41 (100); anal. calcd for C21H15BrСl2N2O (462.17): C 54.57; H 3.27; N 6.06; found: C 54.48; H 3.19; N 6.10.//////////////////////
Clc1ccc(cc1Cl)c2c(cc3CCCn23)C4c5cc(Br)ccc5NC4=O
Angkor Thom, Angkor, Cambodia
ANGKOR RUINS, CAMBODIA
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At Angkor Wat- Templo De Angkor- Siem Reap- Camboya.
Map of the Khmer Empire (in red) in 900 AD
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