1,4-dihydro-4-pyrazolylpyridines and 4-pyrazolylpyridines

compd 3d

Synthesis and antimicrobial evaluation of new 1,4-dihydro-4-pyrazolylpyridines and 4-pyrazolylpyridines

Om Prakash¹, Khalid Hussain², Ravi Kumar^3*, Deepak Wadhwa⁴, Chetan Sharma⁵ and Kamal R Aneja⁵

• *Corresponding author: Ravi Kumar ravi.dhamija@rediffmail.com

Author Affiliations

¹Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra 136 119, India ²Department of Chemistry, Guru Nanak Khalsa College, Yamunanagar 135001, India ³Department of Chemistry, Dyal Singh College, Karnal 132 001, India ⁴Department of Chemistry, Kurukshetra University, Kurukshetra 136 119, India ⁵Department of Microbiology, Kurukshetra University, Kurukshetra 136 119, India

Organic and Medicinal Chemistry Letters 2011, 1:5  doi:10.1186/2191-2858-1-5

 http://www.orgmedchemlett.com/content/1/1/5  

 

Graphical abstract

  SCHEME   Mech Scheme 2 Proposed mechanism for the oxidation of 2 to 3.

 3d: M.p.: 121°C; yield: 70%; IR (ν_max, cm^-1, KBr): 1728, 1236, 1037; ¹H NMR (CDCl₃, δ, ppm): 0.924-0.971 (t, 6 H), 2.615 (s, 6 H), 3.905-4.105 (q, 4 H), 6.987-7.044 (m, 2 H), 7.280-7.365 (m, 1 H), 7.469-7.622 (m, 4 H), 7.733-7.759 (d, 2 H, J = 7.8 Hz), 7.923 (s, 1 H); mass: m/z 488.36 (M⁺ + 1, 100%). Anal. Calcd for C₂₈H₂₆N₃O₄F: C 68.99, H 5.38, N 8.62; found: C 68.95, H 5.37, N 8.63.  


   Institute of Pharmaceutical Sciences, Kurukshetra University,       Bronze Chariot with Lord Krishna and Arjuna in Kurukshetra. Heritage Hotel       Bhisham Kund Narkatari, Kurukshetra Kurukshetra Kurukshetra museum

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

COCK WILL TEACH YOU NMR

COCK SAYS MOM CAN TEACH YOU NMR

DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO .....FOR BLOG HOME CLICK HERE

http://newdrugapprovals.org/

Join me on Linkedin

Join me on Facebook FACEBOOK

Join me on twitter     

Join me on google plus Googleplus

         

 amcrasto@gmail.com