Carboxylative cyclization of substituted propenyl ketones using CO2: transition-metal-free synthesis of [small alpha]-pyrones

Carboxylative cyclization of substituted propenyl ketones using CO2: transition-metal-free synthesis of [small alpha]-pyrones

Green Chem., 2016, 18,4181-4184

DOI: 10.1039/C6GC01346E, Communication

Wen-Zhen Zhang, Ming-Wang Yang, Xiao-Bing Lu
Carboxylative cyclization of substituted 1-propenyl ketones via [gamma]-carboxylation using CO₂ provides an efficient, straightforward, and transition-metal-free access to [small alpha]-pyrone compounds.

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC01346E?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract

Carboxylative cyclization of substituted propenyl ketones using CO₂: transition-metal-free synthesis of α-pyrones

Wen-Zhen Zhang,*^a   Ming-Wang Yang^a and   Xiao-Bing Lu^a  

*Corresponding authors

^aState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, P. R. China
E-mail: zhangwz@dlut.edu.cn

Green Chem., 2016,18, 4181-4184

DOI: 10.1039/C6GC01346E

 

Carbon dioxide is a green carboxylative reagent due to its non-toxic and renewable properties. Described herein is a carboxylative cyclization of substituted 1-propenyl ketones via γ-carboxylation using CO₂, which provides an efficient, transition-metal-free and straightforward access to important α-pyrone compounds from easily available substrates and CO₂.

 

 

////////////Carboxylative cyclization, substituted propenyl ketones, CO2,  transition-metal-free synthesis,  [small alpha]-pyrones