An efficient Passerini tetrazole reaction (PT-3CR)

An efficient Passerini tetrazole reaction (PT-3CR)

Green Chem., 2016, 18,3718-3721
DOI: 10.1039/C6GC00910G, Communication

Ajay L. Chandgude, Alexander Domling
A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed.

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC00910G?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract

A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed. It comprises the reaction of an aldehyde/ketone, an isocyanide and a TMS-azide in methanol:water (1:1) as the solvent system. The use of sonication not only accelerated the rate of the reaction but also provided good to excellent quantitative yields. This reaction is applicable to a broad scope of aldehydes/ketones and isocyanides.

An efficient Passerini tetrazole reaction (PT-3CR)

Ajay L. Chandgude^a and   Alexander Dömling*^a  

*

Corresponding authors

^a

Department of Drug Design, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
E-mail: a.s.s.domling@rug.nl
Web: http://www.drugdesign.nl/

Green Chem., 2016,18, 3718-3721

DOI: 10.1039/C6GC00910G

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Brest, Bretagne, France


Brest is a city in the Finistere department in Brittany in Northwestern France & is an important harbour and second French military port after Toulon...

Brest

City in France

Brest is a city in the Finistère département in Brittany in northwestern France. Located in a sheltered position not far from the western tip of the Breton peninsula, and the western extremity of ... Wikipedia

'The Musee de la Tour Tanguy' in the Tanguy Tower, houses a collection of dioramas that depict the city of Brest on the eve of World War II... — Brest, Bretagne.

Bridge of Recouvrance



Bridge of Recouvrance on the river Penfeld... 



The castle hosts the Musée national de la Marine (National Navy Museum).. 



The castle hosts the Musée national de la Marine (National Navy Museum). 




One Brest inhabitant in ten is a student. With 26 000 students, over 2000 of whom are foreign, Brest metropolis leaves no room for doubt: the surroundings, ...










Brest-Bretagne International Airport Terminal













The Phare du Petit Minou is a lighthouse in the roadstead of Brest in the commune of Plouzané in Brittany (Bretagne). It is located near the Minou fort that ...




Musée national de la Marine






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Oxidation of refractory sulfur compounds with molecular oxygen over a Ce-Mo-O catalyst

Oxidation of refractory sulfur compounds with molecular oxygen over a Ce-Mo-O catalyst

Green Chem., 2016, Advance Article
DOI: 10.1039/C6GC01357K, Paper

Yawei Shi, Guozhu Liu, Bofeng Zhang, Xiangwen Zhang
A Ce-Mo-O catalyst showed remarkable performance for aerobic oxidative desulfurization without sacrificial agents at 100 [degree]C and atmospheric pressure.

Oxidation of refractory sulfur compounds with molecular oxygen over a Ce–Mo–O catalyst

Yawei Shi,^a   Guozhu Liu,*^a   Bofeng Zhang^a and  Xiangwen Zhang*^a  

*

Corresponding authors

^a

Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Collaborative Innovation Centre of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China
E-mail: gliu@tju.edu.cn, zhangxiangwen@tju.edu.cn
Fax: +86 22 27892340
Tel: +86 22 27892340

Green Chem., 2016, Advance Article

DOI: 10.1039/C6GC01357K

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC01357K?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract


A Ce–Mo–O catalyst prepared by a simple sol–gel method was proved to be highly active for aerobic oxidative desulfurization. Almost complete conversions of dibenzothiophene and 4,6-dimethyldibenzothiophene were achieved without any additional sacrificial agent at 100 °C and atmospheric pressure, and the conversion of benzothiophene could reach 97%. Reusability of the catalyst was also conducted, and >99% conversions could be achieved in three consecutive runs. As supported by carefully-designed control experiments, oxygen was activated by Ce species in the catalyst first, forming some reactive oxygen species, which oxidized DBT into DBTO₂ with the assistance of Mo species. Furthermore, selective quenching experiments indicated the generation of superoxide species during the reaction.





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BERMUDA

Bermuda

British Overseas Territory

Bermuda is a British island territory in the North Atlantic, off the eastern U.S., known for its distinctive blend of British and American culture and pink-sand beaches such as Elbow Beach and Horseshoe Bay. Its massive Royal Naval Dockyard complex combines modern attractions like the interactive Dolphin Quest with a look at maritime history at the National Museum of Bermuda.

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Visible-light-activated copper(I) catalyzed oxidative Csp–Csp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

A novel visible-light-promoted copper-catalysed process for the C_sp–C_sp cross-coupling reaction of terminal alkynes at room temperature is described. The current photochemical method is simple, highly functional group compatible, and more viable towards the construction of bio-active 1,3-unsymmetrical conjugated diynes without the need of bases/ligands, additives and expensive palladium/gold catalysts.

Visible-light-activated copper(I) catalyzed oxidative Csp-Csp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

 

Green Chem., 2016, Advance Article
DOI: 10.1039/C6GC01463A, Communication

Arunachalam Sagadevan, Ping-Chiang Lyu, Kuo Chu Hwang
An efficient and eco-friendly approach to C_sp-C_sp cross-coupling of terminal alkynes for the construction of unsymmetrical conjugated diynes via a visible-light-induced CuCl catalysed process at room temperature is described.

Communication

Visible-light-activated copper(I) catalyzed oxidative C_sp–C_sp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

Arunachalam Sagadevan,^a   Ping-Chiang Lyu^b and  Kuo Chu Hwang*^a  

*Corresponding authors

^aDepartment of Chemistry, National Tsing Hua University, Hsinchu, Republic of China

^bInstitute of Bioinformatics and Structural Biology and College of Life Sciences, National Tsing Hua University, Hsinchu, Republic of China
E-mail: kchwang@mx.nthu.edu.tw
Fax: +886 35711082

Green Chem., 2016, Advance Article

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC01463A?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract
DOI: 10.1039/C6GC01463A

////////Visible-light-activated,  copper(I) catalyzed,  oxidative C_sp–C_sp cross-coupling reaction,  unsymmetrical conjugated diynes 

Munjeet, Pakistan

Munjeet

Pakistan

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3-O-(3-Nitrobenzoyl)-4,6-O-benzylidene-1-deoxy-1-(2-oxo-2-phenylethyl)-β-D-glucopyranose

 Nuclear Overhauser effect observed


3-O-(3-Nitrobenzoyl)-4,6-O-benzylidene-1-deoxy-1-(2-oxo-2-phenylethyl)-β-D-glucopyranose (8b).


 White solid, mp 108-110 ºC, Rf  (petroleum ether/EtOAc, 2:1) = 0.23,

1H NMR (500 MHz, CDCl3) 8.78 (1H, s, Ar H), 8.52-8.24 (2H, m, Ar H), 7.87 (2H, d, J 7.3 Hz, Ar H), 7.63 (1H, t, J 8.0 Hz, Ar H), 7.56-7.46 (3H, m, Ar H), 7.46-7.29 (5H, m, Ar H), 5.55 (1H, s, Ph-CH), 5.28 (1H, t, J 9.4 Hz, H-3′), 4.46 (1H, ddd, J 10.2, 8.0, 3.5 Hz, H-1′), 4.34 (1H, dd, J 10.1, 3.7 Hz, H-6′a), 4.12 (1H, q, J 7.2 Hz, H-6′b), 3.78-3.52 (3H, m, H-5′, H-4′, H-2′), 3.38 (1H, dd, J 16.7, 7.9 Hz, H-1′a), 3.04 (1H, dd, J 16.7, 3.5 Hz, H-1′b).


13C NMR (125 MHz, CDCl3) 196.6, 164.1, 147.1, 135.7, 134.6, 128.6, 128.0, 127.5, 127.2, 127.1, 126.6, 125.0, 123.7, 100.4, 77.5, 75.8, 75.6, 72.6, 69.7, 67.6, 40.1.

HRMS (ESI): calcd for C28H25NO9Na: m/z 542.1422 [M + Na]+ ; found 542.1418.


ARKIVOC Volume 2016

Selective acylation and sulfonylation of 4,6-O-benzylidene-1-deoxy-1-(2-oxo-2-phenylethyl)-β-D-glucopyranose (JY-9345IP) 
Xiaomin Gu and Zhijie Fang
Full Text: PDF (363K)
pp. 233 - 249 
received Jul 16 2015; accepted Nov 27 2015; published Dec 17 2015;
Selective acylation and sulfonylation of 4,6-O-benzylidene-1-deoxy- 1-(2-oxo-2-phenylethyl)-β-D-glucopyranose Xiaomin Gu and Zhijie Fang* School of Chemical Engineering, Nanjing University of Science & Technology, 200 Xiaolingwei St, Nanjing, JiangSu 210 094, P. R. China E-mail: zjfang@njust.edu.cn Dedicated to Jhillu Singh Yadav to mark his outstanding contributions to synthetic organic chemistry
DOI: http://dx.doi.org/10.3998/ark.5550190.p009.345 



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