An efficient Passerini tetrazole reaction (PT-3CR)
http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC00910G?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract
A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed. It comprises the reaction of an aldehyde/ketone, an isocyanide and a TMS-azide in methanol:water (1:1) as the solvent system. The use of sonication not only accelerated the rate of the reaction but also provided good to excellent quantitative yields. This reaction is applicable to a broad scope of aldehydes/ketones and isocyanides.
An efficient Passerini tetrazole reaction (PT-3CR)
*
Corresponding authors
a
Department of Drug Design, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
E-mail: a.s.s.domling@rug.nl
Web: http://www.drugdesign.nl/
E-mail: a.s.s.domling@rug.nl
Web: http://www.drugdesign.nl/
Green Chem., 2016,18, 3718-3721
DOI: 10.1039/C6GC00910G
/////////////Passerini tetrazole reaction (PT-3CR)
Brest, Bretagne, France
Brest is a city in the Finistere department in Brittany in Northwestern France & is an important harbour and second French military port after Toulon...
'The Musee de la Tour Tanguy' in the Tanguy Tower, houses a collection of dioramas that depict the city of Brest on the eve of World War II... — Brest, Bretagne.
Bridge of Recouvrance
Bridge of Recouvrance on the river Penfeld...
The castle hosts the Musée national de la Marine (National Navy Museum)..
The castle hosts the Musée national de la Marine (National Navy Museum).
One Brest inhabitant in ten is a student. With 26 000 students, over 2000 of whom are foreign, Brest metropolis leaves no room for doubt: the surroundings, ...
Brest-Bretagne International Airport Terminal
The Phare du Petit Minou is a lighthouse in the roadstead of Brest in the commune of Plouzané in Brittany (Bretagne). It is located near the Minou fort that ...
Musée national de la Marine
/////////
No comments:
Post a Comment