DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Friday 19 February 2016

S -PANTOPRAZOLE

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The chemical formulae of omeprazole, lansoprazole, rabeprazole and pantoprazole represented as:

Lansoprazole                                                                                                   Pantoprazole






Pantoprazole


Select A Method:
Pantoprazole
  • Column:
  • (R,R) or (S,S)-alpha-Burke 2 5 µm 25 cm x 4.6 mm

  • Method:
  • Chiral Separations by HPLC

  • Regis Catalog Number:
  • 1-735035-300; 1-735037-300

  • CAS#:
  • 102625-70-7
Pantoprazole
  • Column:
  • RegisPack 5 µm 25 cm x 4.6 mm

  • Method:
  • Chiral Separations by HPLC

  • Regis Catalog Number:
  • 1-783104-300

  • CAS#:
  • 102625-70-7
Pantoprazole
  • Column:
  • RegisPack, 5 µm, 25 cm x 4.6 mm

  • Method:
  • Chiral Separations by SFC

  • Regis Catalog Number:
  • 1-783104-300

  • CAS#:
  • 102625-70-7

PANTOPRAZOLE


Title: Pantoprazole
CAS Registry Number: 102625-70-7
CAS Name: 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
Manufacturers' Codes: SKF-96022; BY-1023
Molecular Formula: C16H15F2N3O4S
Molecular Weight: 383.37
Percent Composition: C 50.13%, H 3.94%, F 9.91%, N 10.96%, O 16.69%, S 8.36%
Literature References: Gastric proton pump inhibitor. Prepn: B. Kohl et al., EP 166287; eidem, US 4758579 (1986, 1988 both to Byk Gulden); eidem, J. Med. Chem. 35, 1049 (1992). Mechanism of action: W. A. Simon et al., Biochem. Pharmacol. 39, 1799 (1990). HPLC determn in plasma and serum: R. Huber et al., J. Chromatogr. 529, 389 (1990). Clinical pharmacokinetics: B. Simon et al., Z. Gastroenterol. 28, 443 (1990). Clinical trial in duodenal ulcer: P. Müller et al., ibid. 30, 771 (1992); in Zollinger-Ellison syndrome: E. A. Lew et al., Gastroenterology 118, 696 (2000). Review of pharmacology and clinical experience: P. Poole, Am. J. Health-Syst. Pharm. 58, 999-1008 (2001).
Properties: Off-white solid, mp 139-140° (dec). pKa1 3.92; pKa2 8.19.
Melting point: mp 139-140° (dec)
pKa: pKa1 3.92; pKa2 8.19
 
Derivative Type: Sodium salt
CAS Registry Number: 138786-67-1
Trademarks: Eupantol (Altana); Pantecta (Pfizer); Pantozol (Altana); Pantopan (Pharmacia); Pantorc (Altana); Peptazol (Recordati); Protium (Altana); Protonix (Wyeth); Somac (Pfizer)
Molecular Formula: C16H14F2N3NaO4S
Molecular Weight: 405.35
Percent Composition: C 47.41%, H 3.48%, F 9.37%, N 10.37%, Na 5.67%, O 15.79%, S 7.91%
Properties: Prepd as the sesquihydrate. White to off-white crystalline powder, dec >130°. uv max (methanol): 289 (e 1.64 ´ 104). Freely sol in water; very slightly sol in phosphate buffer (pH 7.4). Practically insol in n-hexane.
Absorption maximum: uv max (methanol): 289 (e 1.64 ´ 104)
 
Therap-Cat: Antiulcerative; in treatment of Zollinger-Ellison syndrome.
Keywords: Antiulcerative; Gastric Proton Pump Inhibitor.

http://shodhganga.inflibnet.ac.in/bitstream/10603/2173/12/12_chapter%205.pdf
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 PESHAWAR, PAKISTAN FOOD


Peshawar is one the oldest cities of South Asia. It is an entrance point of Pakistan from the Afghanistan. It was an important city of Subcontinent and a meeting and marketing place for the public of Middle East, India and central Asia. Afghan warriors used this way to enter into subcontinent.
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NALLI GOSHT

Pakistani cooks prepare food for refugees in the Jalozai camp in Peshawar,






Food being prepared at Qissa Khuwani Bazaar in Peshawar on the eve of Eid Milad-

The Big Pot Tea Man of Peshawar







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