(5-Methyl-1,3,4-thiadiazol-2-yl)methylamine hydrochloride
Hydrogen chloride gas was bubbled through an ice-cooled solution of the thiadiazole from preparation 14 (425 mg, 1.85 mmol) in dichloromethane (50 ml) for 15 minutes, and the reaction stirred at room temperature for 1 hour. The mixture was purged with nitrogen, then evaporated under reduced pressure to afford the title compound as a white solid;
1H NMR (DMSOd6, 400 MHz) δ: 2.75 (s, 3H), 4.48 (m, 2H), 8.80 (bs, 3H).
