DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution
Showing posts with label ML 404. Show all posts
Showing posts with label ML 404. Show all posts

Friday, 26 June 2015

ML404 (KSC-392-065)


ML404.

ML404


1H NMR Spectrum (400 MHz, Acetone-d6) of the Probe CID72199308, KSC-392-065.

1H NMR Spectrum (400 MHz, Acetone-d6) of the Probe CID72199308, KSC-392-065

13C NMR (101 MHz, Acetone-d6) δ 172.82, 160.59, 159.11, 158.03, 151.30, 137.76, 132.82, 132.07, 131.58, 130.67, 128.96, 126.42, 124.48, 119.08, 118.30, 113.52, 100.39, 17.49.
 HRMS calcd for (C17H13ClN2O3 −[H]): 327.0542, found: 327.0538.


 ML404.


 ML404(KSC-392-065)

 N-(5-chloro-2-methylphenyl)-5-(3-hydroxyphenyl)isoxazole-3-carboxamide (55 mg, 0.167 mmol, 43 % yield) as a white solid.  



1H NMR (400 MHz, Acetone-d6) δ 9.19 (s, 1H), 7.95 (d, J = 2.3 Hz, 1H), 7.50–7.37 (m, 3H), 7.32 (d, J = 8.2 Hz, 1H), 7.23 (s, 1H), 7.19 (dd, J = 8.2, 2.3 Hz, 1H), 7.03 (ddd, J = 7.9, 2.4, 1.2 Hz, 1H), 2.38 (s, 3H).  



13C NMR (101 MHz, Acetone-d6) δ 172.82, 160.59, 159.11, 158.03, 137.76, 132.82, 132.07, 131.58, 130.67, 128.96, 126.42, 124.48, 119.08, 118.30, 113.52, 100.39, 17.49.


HRMS (ESI) m/z calcd for (C17H13ClN2O3 −[H]): 327.0542, found: 327.0538.


UPLC purity at 214 nm is 99%.


 

Best street food cities in Asia


Best street food cities in Asia

Asia is famous for its impossibly delicious street food, but which cities should be on your culinary bucket list? From must-eat dishes to iconic night markets, here is Skyscanner’s guide to Asia’s best street food cities. Hungry yet?


1. HanoiVietnam

Hanoi’s Old Quarter is a foodie paradise, with hundreds of colourful stalls overflowing into a maze of streets. As you eat your way through this vibrant neighbourhood, here are some delicacies to look out for. Tucking into a steaming bowl of beef or chicken pho is a quintessential Hanoi experience; but the real hero of street food isbun cha, a heavenly dish of barbecued pork served with rice noodles and fragrant fish sauce. Another decadent snack is nem cua be – crispy spring rolls stuffed with delicious crabmeat. After feasting like a king, don’t forget to indulge in Hanoi’s most exquisite treat: iced coffee with sweetened condensed milk, also known as ca phe sua da.
 
Read more: 7 ideas for the 7 Singapore long weekends this 2015
Eating on the sidewalk is a Hanoi tradition. Photo credit: Paul Galow / Flickr

Photo credit: Paul Galow

2. BangkokThailand

Bangkok is famous for its dizzying array of delectable street food, so where do you even start? If you’re a newbie, head to Sukhumvit Soi 38, a bustling road that offers the perfect introduction to Bangkok’s eclectic food scene. You can’t go wrong with pad see ew, a sinfully tasty dish of stir-fried noodles, dark soy sauce, and scrambled egg; or how about snacking on grilled pork skewers marinated in coconut milk (moo ping)?
For dessert, gorge on banana fritters, luscious mangosteens, or the ubiquitous mango sticky rice. Avid eaters should continue their food adventures at Yaowarat (Bangkok’s Chinatown), Banglamphu and Wang Lang Market. Warning: you might never leave.
 
Read more: Rediscover Bangkok in Instagram pictures
Dive into Bangkok's foodie paradise! Photo credit: Austronesian Expeditions / Flickr

Photo credit: Austronesian Expeditions

3. PenangMalaysia

Penang is a melting pot of Chinese, Malay and Indian cultures, so it’s no wonder that it boasts some of the world’s best street food. Although you’re guaranteed to eat well in virtually every corner of Penang, the charming city of George Town is your gateway to hawker heaven. Don’t miss the iconic assam laksa, a tangy fish-based soup infused with tamarind and chilli, or the salty-sweet perfection of rojak. Other swoon-worthy dishes include curry noodles, roti canai, and Penang’s unbeatable version of char kway teow.
Overwhelmed by all this culinary goodness? Hop on one of George Town’s many street food tours for the ultimate sensory feast.
 
Read more: 6 best family hotels in Penang
Don't leave Penang without trying assam laksa! Photo credit: Daniel Chong Kah Fui / Flickr



4. TaipeiTaiwan

Exploring Taipei’s legendary night markets is like diving into a sea of rich flavours. From savoury oyster omelettes to grilled squid skewers, the street food scene is out of this world. Treat your taste buds to scrumptious pork belly buns (gua bao), or an epic bowl of braised beef noodles. And now for the real challenge: are you brave enough to try stinky tofu? If that potent snack is too much to handle, you can opt for another quirky Taiwanese specialty: deep-fried milk on a stick!
For a truly authentic experience, head to Raohe, Ningxia or Shilin night markets. Is there anything better than noshing on gloriously cheap food until the wee hours of morning?
 
Read more: 9 best things to do in Taipei
It's skewers galore at Taipei's night markets! Photo credit: Aaron Shumaker / Flickr

Photo credit: Aaron Shumaker

5. FukuokaJapan

Fukuoka should be on every serious foodie’s list, if only for its famously divine tonkotsu ramen. When you try this mouth-watering combination of silky noodles and creamy pork-based broth, you just might shed tears of joy. Fukuoka is known for its myriad of lively open-air food stalls that only open at dusk. These yatai act as pop-up restaurants, serving delicious fare like yakitori and tempura, along with generous doses of sake.
Although you’re likely to bump into a yatai at every turn, the best ones can be found in the districts of Tenjin and Nakasu. Don’t leave Fukuoka without tasting iwashi mentaiko – grilled Japanese sardines stuffed with spicy pollock roe. This is street food at its best.
 
Read more: 7 must-try cocktail bars in Asia Pacific
Experience Fukuoka's unique food stalls. Photo credit: drufisher / Flickr

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