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Showing posts with label arginine conjugates and peptides. Show all posts
Showing posts with label arginine conjugates and peptides. Show all posts

Saturday, 7 November 2015

Arginine thioacid in synthesis of arginine conjugates and peptides

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Protected arginine thioacid enables convenient N-acylation with no detectable racemization. We report efficient syntheses of potentially biologically active arginine conjugates and novel arginine-containing di-, tri- and tetrapeptides in good yields without loss of chiral integrity.


Graphical abstract: Arginine thioacid in synthesis of arginine conjugates and peptides





Arginine thioacid in synthesis of arginine conjugates and peptides

*Corresponding authors
aCenter for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, USA
E-mail: ravilx84@gmail.com, charlesdennishall@gmail.com
Tel: +1-352-392-0554
bCenter of Excellence for Advanced Material Research, King Abdulaziz University, Jeddah, Saudi Arabia
c
Department of Chemistry, King Abdulaziz University, Jeddah, Saudi Arabia
RSC Adv., 2014,4, 55210-55216

DOI: 10.1039/C4RA04897K

 http://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra04897k#!divAbstract






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