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Showing posts with label or 3. Show all posts
Showing posts with label or 3. Show all posts

Saturday 7 November 2015

Tris(3-pyridyl)boroxin: Pyridine, or 3,3',3"-(2,4,6-boroxintriyl)tris-; cas (160688-99-3)

An Improved Protocol for the Preparation of 3-Pyridyl- and Some Arylboronic Acids

Process Research Department, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065 wenjie_li@merck.com; dorian_nelson@merck.com
J. Org. Chem., 2002, 67 (15), pp 5394–5397
DOI: 10.1021/jo025792p
Publication Date (Web): June 13, 2002
Copyright © 2002 American Chemical Society

Abstract

Abstract Image
3-Pyridylboronic acid was prepared in high yield and bulk quantity from 3-bromopyridine via a protocol of lithium−halogen exchange and “in situ quench”. This technique was further studied and evaluated on other aryl halides in the preparation of arylboronic acids. 
 paper
 http://www.orgsyn.org/demo.aspx?prep=v81p0089
 .


 

4 ............... tris(3-pyridyl)boroxin

 Tris(3-pyridyl)boroxin:
Pyridine, 3,3',3"-(2,4,6-boroxintriyl)tris-; (160688-99-3)


compd4=   The checkers obtained trispyridylboroxin in various hydration levels (0.85 - 1.0 H2O). A satisfactory melting point for this solid could not be obtained. 1H NMR pdf (400 MHz, CD3OD): δ 7.66 (br s, 1H), 8.38 (d, J=6.6, 1H), 8.51 (dd, J=1.2, 4.4, 1H), 8.61 (br s, 1 H). 1H NMR spectra were complicated in other solvents such as CDCl3 and DMSO-d6. Anal Calcd. for C15H12B3O3N3 · 1.0H2O: C, 54.15; H, 4.24; N, 12.63. Found: C, 53.95; H, 3.91; N, 12.35. Yield based on this formula is 85%. The submitters report obtaining the product in 91% yield.







GOA, INDIA,


Whether you’re a fan of relaxing brunches, fancy a quick snack in between shopping or just love a late afternoon cream tea, Goa has got the cafe to suit your mood. Just check out  recommendations for a great treat out on your next Goa holiday.

1. Cafe Lovii, Margao

Welcome to the city’s latest secret, tucked in a hideaway just next to Margao’s Old Judicial Court garden. Cafe Lovii’s selection of healthy wraps, delicious sandwiches and nutritious shakes provide a refreshing alternative to the city’s usual bustling eateries with poky corners and packed tables for the lunch-time crowd. It’s a great place for late brunch – try the quail eggs omelette and the delectable Fruit Tower with lashings of yoghurt to top it off. You can get a filling meal for under INR 200 here. 
 

 
Have a refreshing shake at Cafe Lovii.
Photo credit: www.burrp.com
 

2. Urban Cafe, Panaji

Tucked away in Panjim’s Latin Quarter is this cosy, two floor hide-out that has become the favourite hang-out for freelancers and solo travellers.The ground floor space is light-filled and welcoming but you can head upstairs for a cosier ambience with dim lights, dark walls and bottomless sofas that suck you in and never want to let you go. This is a great stopover for a cold coffee, a brownie and a long chat with your best buddy. Pssst... There’s a magazine rack full of great reads. A drink and a brownie will cost you around INR 250.
 

After a coffee at the Urban Cafe, enjoy a stroll around Goa's famous Latin Quarter
 

3. Ruta's, Mapusa

If you’re dying for a decent cappuccino and sandwich in the area, then Ruta’s is your best bet. Located next to FabIndia, it’s a great stopover in between shopping. Try the Quesadilla if you’re in the mood for melted cheese and don’t leave without trying the Sticky buns. You’ll be craving it even after the last morsel is gone. Coffee and a main dish will cost you about INR 600.
 

Pop by Ruta's if you're in the Mapusa area.
Photo credit: www.zomato.com
 

4. Baker's Studio, Baga

Craving a great morning fry-up that you don’t have to make yourself? Then head over to Baker’s studio in Tito’s lane, Baga. It’s great for taking the edge off those morning-after hangovers and sliding slowly into your day after a hard night of Goa-style partying. Order a lip-smacking British fry-up with fried eggs on toast, two slices of bacon, sausage, beans, mushrooms and a slow-cooked tomato to top it off, all for just INR 300.
 

This is the place to visit if you want tasty fuel for your busy morning.
Photo credit: www.whatsupgoa.com
 

5. Bodega, Panaji

If you’re looking for a quiet, artsy place with a bit of romance to it (and free wifi), you can’t go wrong with Cantina Bodega set atop Altinho. Lining the courtyard of Sunaparanta – Goa Centre for the Arts, it’s the perfect place to go for a breezy catch-up with friends or a comforting break after a hectic week. You can even drop in for a late Sunday breakfast here with waffles, pancakes and even Eggs Benedict to order. Or you can settle in for a pizza or fresh salad. Some say the red velvet cupcakes are to die for! A meal costs roughly INR 600.
 
Head to Bodega if you like your coffee and snack with a side of art.
Photo credit: www.sgcfa.org
 

6. Cherry Tomato Cafe at Carpe Diem, Majorda

This little art cafe is buried in the heart of Majorda, deep in the annals of a nineteenth century Portuguese mansion. The renovated old place now houses Carpe Diem, an art centre that exhibits paintings and holds workshops and creative events of all types. It also has one of the best cafes in South Goa, with a smattering of tables in the little garden at the back, surrounded by works of art on display. Order the Boozy Banana shake as a starter and the Cubano pulled pork sandwich as a follow-up for about INR 450 together. You’ll need a short nap after to recover from your tasty meal!
 
Enjoy the hip atmosphere around you while sip a delicious smoothie.
Photo credit: www.carpediemgoa.com
 

7. Lila Cafe, Anjuna

The thatched roof and bamboo chairs give it a picturesque, light, airy setting and a real laid back feel to this little gem, located on the Calangute-Arpora-Siolim road. Delicious, buttery croissant sandwiches are the mouth-watering munchies to order here. But there’s plenty of other food to tempt the palate with hot breakfasts, tempting smoothies and finger-licking apple pie on the menu too. It’s the kind of place to pick if you want somewhere quiet to read your latest novel or want to meet up with friends for a good gossip session. 
 
The welcoming entrance to Lila Cafe draws you in.
 

8. Cafe Chocolatti, Candolim

When you think of Cafe Chocolatti, think of ordering the cream tea complete with home-made scones and fresh strawberry jam. The cafe is nestled within a high walled garden, giving it a secluded feel where you can just get away from the hustle and bustle for a few hours while you grab a light lunch or a snack and a coffee. A spinach and mushroom savoury crepe with a chocolate shake will cost just under INR 500.
 

 
Two words...Chocolate. Cake. Enough said?
 

9. Natti's Naturals, Arpora

This health food store has an organic cafe that all health-conscious folks will love. You’ll find it on a quiet stretch along the Anjuna-Calangute route. The outdoor cafe is decked in pastels and white, reflecting the sense of calm and serenity that permeates the entire property. The cafe adjoining the store serves salads, burgers, gluten-free desserts and fresh fruit juices combining unique aromatic flavours.
 
Enjoy the minimalist chic decor and surroundings of Nattis Naturals.
Photo credit: www.whatshot.in

 

10. Thirsty Bear, Panaji

Right on the Bambolim highway, just a stone’s throw from the Goa Dental College, is the Thirsty Bear. It’s a great stop for a waffle-with-ice-cream brunch, a luscious chocolate milk shake or a quick thin crust pizza. But it is more the kind of place where you stop when you’re in a bit of a rush but still want a tasty sit-down breakfast to fuel you up for a busy day. And best of all...its open 24-hours a day! A drink and a bite will cost you just under INR 500. 
 
Pop by anytime into the Thirsty Bear for a tasty snack - day or night.
Photo credit: www.blog.sagmart.com













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