Favipiravir

• Molecular FormulaC5H4FN3O2
• Average mass157.103 Da

SYNTHESIS AT https://newdrugapprovals.org/2015/08/18/filgotinib/

259793-96-9 [RN]

2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-

 

6-Fluoro-3-hydroxypyrazine-2-carboxamide

6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxamide

 

8916

Avigan

ファビピラビル
Favipiravir

SYN

https://link.springer.com/article/10.1007/s11696-018-0654-9

Electronic supplementary material

 

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 1315 kb)

Ref

https://pdfs.semanticscholar.org/be8e/cb882b99204983d2f60077c7ab8b53f4d62c.pdf

Drug Discoveries & Therapeutics. 2014; 8(3):117-120.

 mp = 178-180°C. 1 H-NMR (600 MHz, DMSO): δ 12.34 (brs, 1H, OH), 8.31 (d, 1H, pyrazine H, J = 8.0 Hz), 7.44 (s, 1H, CONH2), 5.92 (s, 1H, CONH2). 13C-NMR (75 MHz, DMSO): δ 168.66, 159.69, 153.98, 150.76, 135.68. HRMS (ESI): m/z [M + H]+ calcd for C5H5FN3O2 + : 158.0366; found: 158.0360.

PAPER

Chemical Papers (2017), 71(11), 2153-2158.

https://link.springer.com/article/10.1007%2Fs11696-017-0208-6

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 514 kb)

Take a tour

Kerkennah Islands

Kerkennah Islands seen from space
Kerkennah Islands
Geography
Coordinates	34°42′N 11°11′ECoordinates: 34°42′N 11°11′E
Area	160 km2 (62 sq mi)
Administration
Tunisia

Kerkennah Islands (Tunisian Arabic: قرقنة‎ qarqna) are a group of islands lying off the east coast of Tunisia in the Gulf of Gabès, at 34°42′N 11°11′E. The Islands are low-lying, being no more than 13 metres (43 feet) above sea level. The main islands are Chergui and Gharbi. The archipelago has an area of 160 square kilometres (62 sq mi) and a population of 15,501 (2014).^[2]

Kerkennah's main town, Remla (on Chergui), has a population of 2,000. The population of the islands significantly decreased during the 1980s due to drought. The islands were unable to provide suitable irrigation systems and, with clean water rapidly running out, many islanders were forced to leave for mainland Tunisia, the nearest town being Sfax.

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