- Molecular FormulaC5H4FN3O2
- Average mass157.103 Da
SYNTHESIS AT https://newdrugapprovals.org/2015/08/18/filgotinib/
259793-96-9 [RN]
2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-
6-Fluoro-3-hydroxypyrazine-2-carboxamide
6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxamide
8916
Avigan
ファビピラビル
Favipiravir
Favipiravir
SYN
Electronic supplementary material
Below is the link to the electronic supplementary material.
Supplementary material 1 (DOCX 1315 kb)
Ref
Drug Discoveries & Therapeutics. 2014; 8(3):117-120.
mp = 178-180°C. 1 H-NMR (600 MHz, DMSO): δ 12.34 (brs, 1H, OH), 8.31 (d, 1H, pyrazine H, J = 8.0 Hz), 7.44 (s, 1H, CONH2), 5.92 (s, 1H, CONH2). 13C-NMR (75 MHz, DMSO): δ 168.66, 159.69, 153.98, 150.76, 135.68. HRMS (ESI): m/z [M + H]+ calcd for C5H5FN3O2 + : 158.0366; found: 158.0360.
PAPER
Chemical Papers (2017), 71(11), 2153-2158.
Below is the link to the electronic supplementary material.
Take a tour
 Kerkennah Islands seen from space | |
  Kerkennah Islands | |
| Geography | |
|---|---|
| Coordinates | 34°42′N 11°11′ECoordinates: 34°42′N 11°11′E |
| Area | 160 km2 (62 sq mi) |
| Administration | |
| Tunisia | |
Kerkennah Islands (Tunisian Arabic: قرقنة 
qarqna) are a group of islands lying off the east coast of Tunisia in the Gulf of Gabès, at 34°42′N 11°11′E. The Islands are low-lying, being no more than 13 metres (43 feet) above sea level. The main islands are Chergui and Gharbi. The archipelago has an area of 160 square kilometres (62 sq mi) and a population of 15,501 (2014).[2]
Kerkennah's main town, Remla (on Chergui), has a population of 2,000. The population of the islands significantly decreased during the 1980s due to drought. The islands were unable to provide suitable irrigation systems and, with clean water rapidly running out, many islanders were forced to leave for mainland Tunisia, the nearest town being Sfax.
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