5-BROMO-4-(2-IODO-6-METHOXYPHENOXYMETHYL)-2H-1,3-BENZODIOXOLE

1H NMR GRAPH




13C NMR GRAPH








STARTING MATERIALS
FIRST ONE

 

 SECOND ONE



ONE STEP
BEHIND


STILL ONE STEP BEHIND





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 MYRA, TURKEY





 
 


 Demre is a town and its surrounding district in the Antalya Province on the Mediterranean coast of Turkey, named after the river Demre.

Demre is the Lycian town of Myra, the home of Saint Nicholas of Myra, the historical man later developed into the figure of Santa Claus. The district was known as Kale until it was renamed in 2005. http://www.boutiquesmallhotels.com/myra-demre-hotels.html


 
 

 
Myra (Turkey). The theater. And behind, the Lycian tombs.

 

 


 

 

 

 

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3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine.

5.........3-pyridylboronic acid pinacol ester
 3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine.
 Pyridine, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (329214-79-1)

compd5=  obtained the product in 74-82% yield in different runs. The product exhibits the following physical properties: mp 102-105°C; IR (KBr pellet) cm⁻¹ 2994, 2968, 2932, 1609, 1572, 1476, 1410, 1361, 1209, 1154, 1063, 1017, 953, 926, 859, 833, 800, 759, 705; ¹H NMR pdf (500 MHz, CDCl₃): δ 1.33 (s, 12H), 7.25 (ddd, J=1.1, 4.9, 7.5, 1H), 8.03 (dt, J=1.8, 7.5, 1H), 8.64 (dd, J=1.9, 4.9, 1H), 8.93 (d, J=1.1, 1H); ¹³C NMR (126 MHz, CDCl₃) δ 24.8, 84.1, 123.0, 142.2, 152.0, 155.5; MS (EI, 70 eV): 205 (M+, 46), 204 (15), 191 (12), 190 (100), 189 (25), 162 (10), 148 (44), 147 (14), 120 (18), 119 (11), 106 (100), 105 (35), 85 (15), 59 (17), 58 (19); HRMS (EI) m/z 205.1280, calcd for C₁₁H₁₆NO₂B 205.1274. Anal. Calcd for : C₁₁H₁₆BO₂N: C, 64.43; H, 7.86; N, 6.83. Found: C, 64.23; H, 7.99; N, 6.88.

An Improved Protocol for the Preparation of 3-Pyridyl- and Some Arylboronic Acids

Wenjie Li ,* Dorian P. Nelson ,* Mark S. Jensen , R. Scott Hoerrner , Dongwei Cai , Robert D. Larsen , and Paul J. Reider

Process Research Department, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065 wenjie_li@merck.com; dorian_nelson@merck.com

J. Org. Chem., 2002, 67 (15), pp 5394–5397

DOI: 10.1021/jo025792p

Publication Date (Web): June 13, 2002

Copyright © 2002 American Chemical Society

Abstract

3-Pyridylboronic acid was prepared in high yield and bulk quantity from 3-bromopyridine via a protocol of lithium−halogen exchange and “in situ quench”. This technique was further studied and evaluated on other aryl halides in the preparation of arylboronic acids. 

 paper

 http://www.orgsyn.org/demo.aspx?prep=v81p0089

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Tunis, tunisia
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 With Tarek Chelsea at Av. de la Liberté - Lafayette Tunis.


 

 
 Past... — at Carthage Land.

 

 

 

 
 


 

 

 
 

 
  Wisem Djerbien at Hay ennasr tunis.

 
 
 

 
 

 
 

 

 

 

 
 
 

 
 
 

 Les Berges du Lac, Tunis, Tunisia

 

 Alstom low-floor trolley, Place de Barcelona, Tunis, Tunisia

 

 Tunis-Carthage International Airport, Tunisia

 

 Republique Station, Metro leger, Tunis, Tunisia

 

 People walk through the town's main avenue, Avenue Habib Bourguiba.

 

 

 




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