Phylligenin

 Phylligenin

Phenol,4-[(1R,3aS,4S,6aS)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxy-;
Phenol,4-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxy-,[1R-(1a,3aa,4b,6aa)]-;
1H,3H-Furo[3,4-c]furan,phenol deriv.;
(-)-Phylligenin;
Phylligenin;
Phyllygenin;
Symplocosigenolmonomethyl ether

(-)-Phylligenin; 
1H,3H-Furo[3,4-: 23397-47-9. 名 称: Phenol,4-[(1R,3aS,4S,6aS)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxy

C21H24O6
372.00



IR

(KBr) 3450, 1600, 1585, 1510, 1455, 1260



MASS
EIMS m/z (rel. int.) 372 [M]+ (19), 355 (42), 337 (5), 325 (8), 249 (100), 235 (82), 219 (44), 205 (48), 189 (37), 175 (27), 151 (59), 137 (72)










1H NMR

(250 MHz, CDCl3) δ: 6.81-6.91 (6H, m, Ar-H), 5.64 (1H, s, OH), 4.86 (1H, d, J = 5.2 Hz, H-7), 4.42 (1H, d, J = 7.2 Hz, H-7'), 4.13 (1H, d, J = 9.4 Hz, H-9'a), 3.81 (6H, 2 × OCH3), 3.79 (3H, OCH3), 3.58-4.37 (3H, m, H-9, H-9'), 3.21-3.49 (2H, m, H-8', H-9), 2.85 (1H, m, H-8) 13 C NMR (63 MHz, CDCl3) δ: 149.2 (C-3), 148.3 (C-4), 147.1 (C-3'), 145.7 (C-4'), 133.4 (C-1'), 131.3 (C-1), 119.6 (C-6'), 118.1 (C-6), 114.6 (C-5'), 111.3 (C-5), 109.2 (C-2'), 108.9 (C-2),  88.1 (C-7'), 82.4 (C-7), 71.4 (C-9'), 70.1 (C-9), 56.3 (3-OCH3, 4-OCH3, 3'-OCH3), 54.9 (C-8'), 50.5 (C-8) INSTITUTE OF CHEMISTRY UNIVERSITY OF SINDH JAMSHORO INSTITUTE OF CHEMISTRY,  UNIVERSITY OF SINDH,  JAMSHORO, sindh pakistan

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INSTITUTE OF CHEMISTRY UNIVERSITY OF SINDH JAMSHORO















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Food Festival organized by Institute of English Language and Literature UoS , Jamshoro.

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Chorismic Acid

Chorismic Acid

CAS Registry Number: 617-12-9

CAS Name: (3R-trans)-3-[(1-Carboxyethenyl)oxy]-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid

Additional Names: 3-enolpyruvic ether of trans-3,4-dihydroxycyclohexa-1,5-diene carboxylic acid; a-(5-carboxy-1,2-dihydro-2-hydroxyphenoxy)acrylic acid

Molecular Formula: C10H10O6

Molecular Weight: 226.18

Percent Composition: C 53.10%, H 4.46%, O 42.44%

1H NMR

13 CNMR

Literature References: The first branch point intermediate in the biosynthesis of aromatic amino acids via the shikimate pathway in bacteria, fungi, and higher plants; naturally occurring as the (-)-form. Its existence was predicted, then discovered during development of a mutant of A. aerogenes: M. I. Gibson et al., Nature 195, 1173 (1962); M. I. Gibson, F. Gibson, Biochim. Biophys. Acta 65, 160 (1962). NMR and preliminary structure study: F. Gibson, M. Jackman, Nature 198, 388 (1963). Isoln and metabolism study: M. Gibson, F. Gibson, Biochem. J. 90, 248 (1964). Prepn and characterization of the barium salt: F. Gibson, ibid. 256. Structure, relative and abs config, prepn of the monohydrate: J. M. Edwards, L. M. Jackman, Aust. J. Chem. 18, 1227 (1965). Total synthesis of racemic chorismic acid: D. A. McGowan, G. A. Berchtold, J. Am. Chem. Soc. 104, 1153 (1982); B. Ganem et al., ibid. 6787; improved synthesis: G. A. Berchtold et al., ibid. 105, 6265 (1983); short formal synthesis: G. H. Posner et al., J. Org. Chem. 52, 4836 (1987). Total synthesis of (-)-form: J. L. Pawlak, G. A. Berchtold, ibid. 1765. Potential use in development of herbicides: S. Stinson, Chem. Eng. News 60, 31 (Dec. 6, 1982). Reviews of chorismic acid in biosynthesis of aromatic amino acids: F. Gibson, J. Pittard, Bacteriol. Rev. 32, 465-492 (1968); R. J. Ife et al., J. Chem. Soc. Perkin Trans. 1 1976, 1776-1783; U. Weiss, J. M. Edwards, The Biosynthesis of Organic Compounds (Wiley, New York, 1980) pp 134-143. See also shikimic acid.

Properties: Crystals may be obtained but show marked tendency toward solvent retention, mp 105-108° (dec). [a]D21 -274° (c = 0.16 in water).

Melting point: mp 105-108° (dec)

Optical Rotation: [a]D21 -274° (c = 0.16 in water)

 

Derivative Type: Barium salt trihydrate

Molecular Formula: C10H8BaO6.3H2O

Molecular Weight: 415.54

Percent Composition: C 28.90%, H 3.40%, Ba 33.05%, O 34.65%

Properties: Unstable. uv max (aq soln): 272 nm (e 2700).

Absorption maximum: uv max (aq soln): 272 nm (e 2700)

 

Derivative Type: Monohydrate

Properties: Colorless crystals from ethyl acetate + light petroleum, mp 148-149° (dec); from ether + light petroleum, mp 112° (dec); from ethyl acetate + carbon tetrachloride, mp 115° (dec). [a]255890 -295.5° (c = 0.2 in water). uv max (water): 275 nm (e2630).

Melting point: mp 148-149° (dec); mp 112° (dec); mp 115° (dec)

Optical Rotation: [a]255890 -295.5° (c = 0.2 in water)

Absorption maximum: uv max (water): 275 nm (e 2630)

 

Derivative Type: (±)-Form

Properties: Crystals from ethyl acetate/hexane, mp 139.4-141° (dec).

Melting point: mp 139.4-141° (dec)

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METHACRYLIC ACID NMR

Methacrylic acid, or 2-methyl-2-Propenoic acid
C₄H₆O₂

IR









13C NMR

This ¹³C spectrum exhibits resonances at the following chemical shifts, and with the multiplicity indicated:

Shift (ppm)	Mult.
173.7	S
136.1	S
128.0	T
17.6	Q

SEE INTERPRETATION BELOW







1H NMR

Methacrylic acid
IUPAC name[hide] 2-methylpropenoic acid[1]
Other names[hide] MAA, 2-methyl-2-propenoic acid
Identifiers
CAS number	79-41-4
PubChem	4093
ChemSpider	3951
EC number	201-204-4
MeSH	C008384
ChEBI	CHEBI:25219
Jmol-3D images	Image 1
SMILES [show]
InChI [show]
Properties
Molecular formula	C4H6O2
Molar mass	86.06 g/mol
Appearance	Colorless liquid or solid
Odor	Acrid[2]
Density	1.015 g/cm3
Melting point	14 to 15 °C (57 to 59 °F; 287 to 288 K)
Boiling point	161 °C (322 °F; 434 K)
Hazards
NFPA 704	2 3 2
Flash point	77.2 °C (171.0 °F; 350.3 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)