3,3′,5,5′-Tetramethyl-2,2′-biphenol

3,3′,5,5′-Tetramethyl-2,2′-biphenol

10.0 g of 2,4-dimethylphenol.................. of 3,3,′,5,5′-tetramethyl-2,2′-biphenol.¹H NMR (400 MHz, CDCl₃) δ = 7.00–7.03 (m, 2H) 6.87–6.90 (m, 2H), 4.94 (s, 2H, OH), 2.30 (s, 12H). ¹³C NMR (100 MHz, CDCl₃) δ = 149.26, 132.14, 130.14, 128.64, 125.31, 122.30, 20.57, 16.31. Mp: 135 °C. GC purity >98%. Analytical data are in agreement with those previously reported.(37)

Kirste, A.; Nieger, M.; Malkowsky, I. M.; Stecker, F.; Fischer, A.; Waldvogel, S. R. Chem. - Eur. J. 2009, 15,2273– 2277, DOI: 10.1002/chem.200802556

  

• 2,2'-Biphenyldiol, 3,3',5,5'-tetramethyl- (8CI)
• 6,6'-Bi-2,4-xylenol (6CI,7CI)
• 3,3',5,5'-Tetramethyl[1,1'-biphenyl]-2,2'-diol
• 2,2'-Dihydroxy-3,3',5,5'-tetramethylbiphenyl
• 3,3',5,5'-Tetramethyl-2,2'-biphenol

• 3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-2,2'-diol
• 3,3',5,5'-Tetramethylbiphenyl-2,2'-diol

cas 26567-10-2

 

Scalable and Selective Preparation of 3,3′,5,5′-Tetramethyl-2,2′-biphenol

Thomas Quell^†, Nadine Hecken^†, Katrin M. Dyballa^‡, Robert Franke^‡§, and Siegfried R. Waldvogel^*† 

^† Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany

^‡ Evonik Industries AG, Paul-Baumann-Straße 1, D-45772 Marl, Germany

^§ Lehrstuhl für Theoretische Chemie, Ruhr-Universität Bochum, D-44780 Bochum, Germany

Org. Process Res. Dev., Article ASAP

DOI: 10.1021/acs.oprd.6b00356, http://pubs.acs.org/doi/full/10.1021/acs.oprd.6b00356

*E-mail: waldvogel@uni-mainz.de.

P.S. : The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent.

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