Conformational control of anticancer activity: the application of arene-linked dinuclear ruthenium(II) organometallics†

Fig. 3 ¹H NMR spectra of 4a (top) and 5a (bottom) (D₂O, 400 MHz, 298 K, 10 mM).
Resonances are identified with coloured circles: linker phenyl – red, Ru arene – blue, CH – green, PTA – orange, CH₂ – black and CH₃ – purple.

Scheme 1 Synthesis and numbering scheme of the mononuclear oxalato-complex 2a,  dinuclear oxalato-complexes 3a–6a and chlorido-analogues 2b–6b. /////////////////http://pubs.rsc.org/en/content/articlehtml/2014/sc/c4sc00116h/////////////// DRUG APPROVALS BY DR ANTHONY MELVIN CRASTO .....FOR BLOG HOME CLICK HERE Join me on Linkedin Join me on Facebook FACEBOOK Join me on twitter      Join me on google plus Googleplus  amcrasto@gmail.com