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Monday, 12 January 2015

Rubiothiazepine a Novel Unusual Cytotoxic Alkaloid from Ixora undulata Roxb. Leaves

 

compound (1) is 7-[(β-D-glucopyranosyl)oxy]-6- hydroxy-2-methoxy-6,7-dihydro-1,3-thiazepine and trivially named as `Rubiothiazepine` (Structure I).
 

Citation: Mohammed MMD, Ibrahim NA, Chen M, Zhai L (2014) Rubiothiazepine a Novel Unusual Cytotoxic Alkaloid from Ixora undulata Roxb. Leaves. Nat Prod Chem Res 2:128 doi: 10.4172/2329-6836.1000128

http://esciencecentral.org/journals/rubiothiazepine-a-novel-unusual-cytotoxic-alkaloid-from-ixora-undulata-roxb-leaves-2329-6836.1000128.php?aid=24194
Magdy M. D. Mohammed1,2*, Nabaweya A Ibrahim2, Ming Chen3 and Lin Zhai3
1Danish Institute of Agricultural Sciences, Department of Food Science, Research Center Aarslev, Kirstinebjergvej 10, DK-5792 Aarslev, Denmark
2Pharmacognosy Department, National Research Center, Dokki-12311, Cairo, Egypt
3Department of Clinical Microbiology, University Hospital of Copenhagen (Rigshospitalet), Tagensvej 20, DK-2200 Copenhagen N, Denmark
Corresponding Author : Magdy Mostafa Desoky Mohammed
Danish Institute of Agricultural Sciences
Department of Food Science, Research Center Aarslev
Kirstinebjergvej 10, DK-5792 Aarslev, Denmark
Tel: 00201022610332
E-mail: melhenawy111@gmail.com

 
Magdy M. D. Mohammed
Assistant Professor of Chemistry of Medicinal and Aromatic Plants, Pharmacognosy Department






.............
 
Magdy M. D. Mohammed




Assistant Professor of


Chemistry of Medicinal and Aromatic Plants, Pharmacognosy Department




Dikutip olehTahun
Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt
NA Ibrahim, HR El-Seedi, MMD Mohammed
Natural product research 21 (10), 857-866

162007
Anti-HIV-1 and cytotoxicity of the alkaloids of Erythrina abyssinica Lam. growing in Sudan
MMD Mohammed, NA Ibrahim, NE Awad, AA Matloub, AG Mohamed-Ali, ...
Natural product research 26 (17), 1565-1575

62012
Two new phorbol-type diterpene esters from Synadenium grantii Hook f. leaves
EM Hassan, MMD Mohammed, SM Mohamed
Records of Natural Products 6 (3), 255-262

62012
The cytotoxic activity of Linum grandiflorum leaves
MMD Mohammed, M Chen, L Zhai, NA Ibrahim
European Journal of Chemistry 1 (2), 110-114

62010
New acylated flavone and cyanogenic glycosides from Linum grandiflorum
MMD Mohammed, LP Christensen, NA Ibrahim, NE Awad, IF Zeid, ...
Natural product research 23 (5), 489-497

52009
Constituents and biological activity of the chloroform extract and essential oil of Cupressus sempervirens
NA Ibrahim, HR El-Seedi, MMD Mohammed
Chemistry of natural compounds 45 (3), 309-313

42009
Anti-HIV-1 activities of the extracts from the medicinal plant Linum grandiflorum Desf
MMD Mohammed, LP Christensen, NA Ibrahim, NE Awad, IF Zeid, ...
Med. Aroma. Plant Sci. Biotechnol 3, 37-41

32009
Cytotoxic flavonoids from Diplotaxis harra (Forssk.) Boiss. growing in Sinai
MMD Mohammed, ER El-Sharkawy, AA Matloub
Journal of Medicinal Plants Research 7 (1), 19-23

12013
Anti-HIV-1 and cytotoxicity of the alkaloids of Erythrina abyssinica Lam. growing in Sudan
MM Mohammed, NA Ibrahim, NE Awad, AA Matloub, AG Mohamed-Ali, ...
Erratun in Nat Prod Res 27, 295

12013
Cytotoxic flavonoids from Diplotaxis harra (Forssk.) Boiss. growing in Sinai
M Mohammed, ER El-Sharkawy, AA Matloub
JOURNAL OF MEDICINAL PLANTS RESEARCH 5 (20), 5099-5103

12011
Anti-influenza A virus activity of a new dihydrochalcone diglycoside isolated from the Egyptian seagrass Thalassodendron ciliatum (Forsk.) den Hartog
MMD Mohammed, AHA Hamdy, NM El-Fiky, WSA Mettwally, AA El-Beih, ...
Natural product research 28 (6), 377-382

2014
Isolation and anti-HIV-1 activity of a new sesquiterpene lactone from Calocephalus brownii F. Muell.
MMD Mohammed, LP Christensen, PL Colla
Natural product research 28 (4), 221-229

2014
Rubiothiazepine a Novel Unusual Cytotoxic Alkaloid from Ixora undulata
MMD Mohammed, NA Ibrahim, M Chen, L Zhai
Roxb. Leaves. Nat Prod Chem Res 2 (128), 2

2014
Antiviral and cytotoxic activities of anthraquinones isolated from Cassia roxburghii Linn. leaves
M Mohammed, SS El-Souda, SM El-Hallouty, N Kobayashi
Herba Polonica 59 (4), 33-44

2013
4th World Congress on Bioavailability and Bioequivalence: Pharmaceutical R&D Summit
MMD Mohammed

2013
Chemical composition, antimicrobial activity of the essential oil of the flowers of Paulownia tomentosa (Thunb.) Steud. growing in Egypt.
ES Ibrahim, N.A., El-Hawary, S.S., Magdy M. D. Mohammed, Faraid, M.A ...
Journal of Applied Sciences Research 9 (4), 3228-3232

2013
D-mannitol in ameliorating some metabolic disorders in Schistosomal mansoni infected mice.
MMDM Nagy S. El-Rigal, Sanaa A. Ali, Mohga S. Abd-Allah, El-Sayed M. El ...
Egyptian Pharmaceutical Journal 10 (2), 137–166

2011
POTENTIAL ANTICANCER AGENTS FROM LINUM GRANDIFLORUM LEAVES
M Mohammed, M Chen, L Zhai, NA Ibrahim
ANTICANCER RESEARCH 28 (5 C), 3411-3411





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