DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Tuesday 7 June 2016

An efficient Passerini tetrazole reaction (PT-3CR)

Green Chem., 2016, Advance Article
DOI: 10.1039/C6GC00910G, Communication
Ajay L. Chandgude, Alexander Domling
A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed.


An efficient Passerini tetrazole reaction (PT-3CR)


see
http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC00910G?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract

An efficient Passerini tetrazole reaction (PT-3CR)

*
Corresponding authors
a
Department of Drug Design, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands 
E-mail: a.s.s.domling@rug.nl
Web: http://www.drugdesign.nl/
Green Chem., 2016, Advance Article

DOI: 10.1039/C6GC00910G













 A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed. It comprises the reaction of an aldehyde/ketone, an isocyanide and a TMS-azide in methanol : water (1 : 1) as the solvent system. The use of sonication not only accelerated the rate of the reaction but also provided good to excellent quantitative yields. This reaction is applicable to a broad scope of aldehydes/ketones and isocyanides.














  
Ajay L. Chandgude







//////////

 
Nyanza, Rwanda.
 
Map of Nyanza Rwanda
Nyanza
Town in Rwanda
Nyanza is a town located in Nyanza District in the Southern Province of Rwanda. The old Royal Palace of the Rwandan monarchy is located in the town of Nyanza. It is now the Rwesero Art Museum. Wikipedia
 
 
 
 
 
 
 
 
//////////

No comments:

Post a Comment